Can an Intravascular Imaging Modality Detect Really Vulnerable Plaque?
نویسندگان
چکیده
منابع مشابه
POSITRON AUTORADIOGRAPHY FOR INTRAVASCULAR VULNERABLE PLAQUE IMAGING A Thesis
ii ACKNOWLEDGMENTS I extend my thanks to my committee chair, Dr. Polad Shikhaliev, for all his advice and help in research and preparation of this thesis and to all of the members of my supervisory committee: for their assistance and taking time to serve on my supervisory committee. I also thank Shannon Fritz for her selfless help with every aspect of the research project. When it came to the p...
متن کاملCharacterizing vulnerable plaque features with intravascular elastography.
BACKGROUND In vivo detection of vulnerable plaques is presently limited by a lack of diagnostic tools. Intravascular ultrasound elastography is a new technique based on intravascular ultrasound and has the potential to differentiate between different plaques phenotypes. However, the predictive value of intravascular elastography to detect vulnerable plaques had not been studied. METHODS AND R...
متن کاملIntravascular detection of the vulnerable plaque.
Coronary heart disease (CHD) remains the leading cause of death in the United States, and an estimated 1.4 million Americans have a heart attack each year. Over the past 2 decades, the concept of the “vulnerable plaque” (VP) being responsible for the majority of acute coronary syndromes (ACS) has become widely accepted. Coincidentally, there has been rapid expansion of coronary imaging modaliti...
متن کاملMultitarget Vulnerable Plaque Imaging.
The search for the vulnerable plaque has been a prolonged, circuitous journey that despite considerable investment and resource expenditure has hitherto failed to alter clinical practice. The rationale remains enticing. We have known for some time that plaques at risk of rupture and precipitating myocardial infarction and stroke have certain characteristics that extend beyond simple stenosis se...
متن کاملAre there really biomarkers of vulnerable plaque?
The rationale for the search of biomarkers of vulnerable plaques seems sound. Plaque rupture is a key step in the initiation of an acute coronary syndrome (ACS). The atherosclerotic plaque contains large numbers of inflammatory cells that may release hydrolytic enzymes and cytokines, thereby destabilizing the plaque (1 ). Therefore, many inflammatory biomarkers and enzymes have been suggested a...
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ژورنال
عنوان ژورنال: Circulation Journal
سال: 2010
ISSN: 1346-9843,1347-4820
DOI: 10.1253/circj.cj-09-1009